A family's full record
API · /rfam-api
Rfam API
healthy
4,715 Subscribers
The Rfam database of non-coding RNA families as an API, powered by EMBL-EBI. Rfam groups functional RNAs that share a common evolutionary origin into families, each modelled by a covariance model built from a curated seed alignment and secondary structure. Search the families by name, description or RNA type — riboswitches and other cis-regulatory elements, ribozymes, microRNA families, ribosomal RNAs, transfer RNAs, small nuclear and small nucleolar RNAs, long non-coding RNAs and CRISPR direct repeats — getting each family's Rfam accession, name, description, RNA type and curators; read a family's full record including its description, RNA-type classification, the curators who built it, the number of sequences in its full and seed alignments, the structure source, the curator comment, the clan (group of related families) it belongs to and the Rfam release; and browse the families by RNA class. Ideal for RNA biology, bioinformatics pipelines, non-coding-RNA annotation, comparative genomics and teaching. Family accessions look like RF00005 (transfer RNA). Data from EMBL-EBI Rfam. For protein families and domains see the InterPro API, for protein sequences UniProt, for proteomics datasets PRIDE and for metabolomics MetaboLights.
api.oanor.com/rfam-api
API health
healthy- Uptime
- 100.00%
- Server probes · 24h
- Avg latency
- 337 ms
- Server probes · 24h
- Subscribers
- 4,715
- active
- Total calls
- 76
- last 7 days
Pricing
Pick a tier — billed monthly, cancel anytime.
Free
Free
- 560 calls / month
- 2 requests / second
- Hard cap (429 above quota, no overage)
- 560 calls/month
- 2 req/sec
- Search, family & browse
- No credit card
Starter
€6.40 /month
- 20,000 calls / month
- 6 requests / second
- Hard cap (429 above quota, no overage)
- 20k calls/month
- 6 req/sec
- Full family records
- Email support
Pro
€19.80 /month
- 91,000 calls / month
- 15 requests / second
- Hard cap (429 above quota, no overage)
- 91k calls/month
- 15 req/sec
- RNA annotation pipelines
- Priority support
Mega
€55.00 /month
- 378,000 calls / month
- 40 requests / second
- Hard cap (429 above quota, no overage)
- 378k calls/month
- 40 req/sec
- High-throughput comparative genomics
- Dedicated SLA
Built by
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api.oanor.com/dna-api
DNA Melting Temperature API
DNA-oligo and PCR-primer maths as an API, computed locally and deterministically. The tm endpoint computes the melting temperature of a primer sequence three ways: the Wallace rule 2·(A+T) + 4·(G+C) for short oligos up to 13 nt, the Marmur–Wallace GC formula 64.9 + 41·(nGC − 16.4)/N for longer ones, and the salt-adjusted 81.5 + 0.41·%GC − 675/N + 16.6·log10[Na+] for a given sodium concentration, and recommends the right method for the length — an eight-base ATGCATGC melts at 24 °C by Wallace, a 20-base 50 %-GC primer at about 51.8 °C by Marmur. The gc-content endpoint reports the GC and AT percentages, the per-base counts and the single-stranded molecular weight. The reverse-complement endpoint returns the complement, the reverse and the reverse complement of a strand. Sequences use A/C/G/T (case-insensitive, whitespace ignored) and [Na+] is in mol/L. Everything is computed locally and deterministically, so it is instant and private. Ideal for molecular-biology, biotech, PCR, primer-design, bioinformatics and lab-automation app developers, oligo and primer calculators, and LIMS software. Estimation formulas for primer design, not a substitute for nearest-neighbour thermodynamics. Pure local computation — no key, no third-party service, instant. Live, nothing stored. 3 endpoints. This is oligo melting temperature; for population-genetics allele frequencies use a genetics API.
api.oanor.com/dnamelt-api
Genome Assemblies API
Reference genome assemblies as an API — powered by NCBI Assembly, the registry of genome builds for organisms across the tree of life. Search assemblies by organism (or free text) and look up any assembly's metadata: its accession (GCF_… RefSeq or GCA_… GenBank), name (e.g. GRCh38.p14), organism and taxon id, assembly level (complete genome, chromosome, scaffold or contig), contiguity statistics (contig and scaffold N50), sequencing coverage, RefSeq category, UCSC and Ensembl names, the submitting organization, release date and FTP download paths. From the human reference genome to any sequenced microbe, plant or animal, it turns the genome-assembly registry into a clean search-and-fetch API. A genome-assembly registry — distinct from sequence (ENA), genome annotation (Ensembl), variant (ClinVar, dbVar) and gene-expression (GEO) databases. Open data from NCBI Assembly (public domain).
api.oanor.com/genomes-api
Gene Expression API
Functional-genomics experiments as an API — powered by NCBI GEO (Gene Expression Omnibus), the largest public repository of gene-expression data. GEO archives expression series and curated datasets from microarray and high-throughput-sequencing experiments across every organism. Search experiments by keyword and optionally by organism, and look up any series or dataset to get its metadata: title, summary, assay type (expression profiling by array or by sequencing), organism, number of samples, platform and the publication behind it. From β-cell stress studies to cancer transcriptomics across human and mouse, it turns the GEO archive into a simple search-and-fetch API for transcriptomics, bioinformatics and research-data discovery. A gene-expression / functional-genomics dataset repository — distinct from sequence (ENA), variant (ClinVar, dbVar), structure (PDB) and ontology databases. Open data from NCBI GEO (public domain).
api.oanor.com/geodatasets-api
Frequently asked questions
Quick answers about pricing, quotas, and integration.
How do I get an API key for Rfam API?
Sign up for free at oanor.com, generate an API key from the developer dashboard, and call Rfam API with the x-oanor-key header. No credit card needed for the free tier.
What's the rate limit for Rfam API?
Free tier allows 1 request per second. Paid plans scale up to 50 requests per second on the Mega tier. Hard limits return HTTP 429 above the quota — no surprise overage charges.
How much does Rfam API cost?
Rfam API has a free tier with 100 calls / month. Paid plans start at €6.40 / month with higher quotas and faster rate limits.
Can I cancel my subscription anytime?
Yes. Plans are billed monthly and you can cancel anytime from your billing dashboard. No long-term contracts and no cancellation fee.
Is Rfam API GDPR-compliant?
All requests to Rfam API go through our EU-based gateway. Your upstream API key never leaves our server and no personal data is shared with the upstream provider beyond the request you send.
Pick an endpoint from the list on the left to see its details and try it.
Code snippets
Sign up to get an API key, then call any path under your slug.
curl https://api.oanor.com/rfam-api/SOME_PATH \
-H "x-oanor-key: oanor_test_..."const res = await fetch("https://api.oanor.com/rfam-api/SOME_PATH", {
headers: { "x-oanor-key": "oanor_test_..." }
});
const data = await res.json();$ch = curl_init("https://api.oanor.com/rfam-api/SOME_PATH");
curl_setopt($ch, CURLOPT_RETURNTRANSFER, true);
curl_setopt($ch, CURLOPT_HTTPHEADER, ["x-oanor-key: oanor_test_..."]);
$response = curl_exec($ch);import requests
r = requests.get(
"https://api.oanor.com/rfam-api/SOME_PATH",
headers={"x-oanor-key": "oanor_test_..."},
)
print(r.json())Ratings
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